Poststroke Treatment With Selective Serotonin Reuptake Inhibitors

Selective Serotonin Reuptake Inhibitors

It has long been postulated that a deficiency in CNS serotonergic activity is the cause of, or a predisposing factor for, depression. [1] However, the evidence for this association is largely circumstantial and it certainly does not represent an adequate and full model for depression, probably due to there being multiple aetiological factors. [2] Some pharmacological trial data also cast doubt ...

Poststroke treatment with selective serotonin reuptake inhibitors: a journey from sadness to motor recovery.

N umerous studies failed to translate promising experimental data into clinically effective neuroprotective or neurorestorative therapies for acute ischemic stroke since the introduction of recombinant-tissue plasminogen activator in 1996. Amid gloomy pessimism, the results of the fluoxetine for motor recovery after acute ischemic stroke (FLAME) trial in 2011 ignited hope and restored optimism....

Selective serotonin reuptake inhibitors.

Treatment of selective mutism: focus on selective serotonin reuptake inhibitors.

Abstract Selective mutism is a pediatric psychiatric disorder that occurs when a child consistently fails to speak in specific situations in which speaking is expected, such as at school and social gatherings, but speaks appropriately in other settings. Selective mutism often is diagnosed when a child starts school and does not talk to teachers or peers, but talks to family members at home; the...

Aerobic treatment of selective serotonin reuptake inhibitors in landfill leachate

Background: Pharmaceuticals used in human medical care are not completely eliminated in the human body and can enter the municipal sewage sludge system and leachate water from landfill both as the parent compound and as their biologically active metabolites. The selective serotonin reuptake inhibitors (SSRIs) have a large potential for unwanted effects on nontarget organisms in the environment....